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May 7, 2026International Journal of Cardiovascular Sciences0 citationsOpen Access

Myocardial Perfusion Imaging: Always Evolving

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RFR Felix

Key Points

  • This research reviews the evolution of myocardial perfusion imaging and its role in coronary artery disease diagnosis.
  • Reviewed historical development of myocardial perfusion imaging techniques.
  • Discussed the use of radiotracers such as 201-thallium chloride and 99-technetium.
  • Analyzed advancements in imaging technology, including SPECT for three-dimensional visualization.
  • Nuclear medicine established a non-invasive approach for diagnosing coronary artery disease.
  • Diagnostic accuracy of myocardial perfusion imaging has improved with modern tracers and techniques.

Abstract

Myocardial perfusion assessed by nuclear medicine began to be used in clinical practice in the 1970s with the radiotracer 201-thallium chloride in two-dimensional images. Advances in the development of equipment, from the possibility of three-dimensional images by single-photon emission computed tomography (SPECT), and new tracers, such as those linked to 99-technetium, have allowed the consolidation of nuclear cardiology as a non-invasive tool with high diagnostic accuracy in the context of coronary artery disease. … Myocardial Perfusion Imaging: Always Evolving

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R Felix (2026) studied this question.

synapsesocial.com/papers/69fbef86164b5133a91a3602https://doi.org/10.36660/ijcs.20260007
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