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This research aims to evaluate the protective effects of synbiotic supplementation against Salmonella Typhimurium infection in broiler chickens.

May 7, 2026AnimalsOpen Access

Protective Effect of Synbiotic Supplementation Against Salmonella Typhimurium Infection in Young Broiler Chickens

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Trial shows synbiotic reduces inflammation and improves gut health in broiler chickens after Salmonella challenge, indicating protective effects.

This research aims to evaluate the protective effects of synbiotic supplementation against Salmonella Typhimurium infection in broiler chickens.
Conducted an in vivo experiment with 44 broiler chickens assigned to four dietary treatments.
Challenged birds with Salmonella Typhimurium infection at 7 days of age and euthanized at day 12 for sample collection.
Assessed immune response through immunofluorescence analysis and histomorphometry of the ileum.
Synbiotic supplementation reduced bacterial colonization and adhesion in the ileum.
Increased IL-10 expression and decreased pro-inflammatory cytokines IL-1β and TNF-α were observed.
Improved body weight noted in synbiotic-supplemented birds compared to challenged controls.

Pérez et al. (2026) studied this question.

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Trial shows synbiotic reduces inflammation and improves gut health in broiler chickens after Salmonella challenge, indicating protective effects.