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May 7, 2026SpineOpen Access

Cognitive Impairment in Patients with Degenerative Cervical Myelopathy

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Authors

HLHui LiJCJianing CuiJWJiayuan Wu

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Overview

Cross-sectional study reveals cognitive impairment in cervical myelopathy patients, indicating significant spinal cord compression effects.

Key Points

  • Examine cognitive impairment in degenerative cervical myelopathy and its relation to spinal cord compression.
  • Cross-sectional study involving 965 participants across three groups: DCM patients, CSR patients, and healthy controls.
  • Cognitive performance evaluated using MoCA, MMSE, and BCAT.
  • Propensity-score matching was applied to balance demographics and educational background.
  • Radiographic assessments of spinal cord compression were made via cervical MRI and correlation analyses conducted.
  • DCM patients had lower MoCA (20.61) and MMSE (26.23) scores compared to CSR and controls (P < 0.001).
  • Negative correlations were found between maximum spinal cord compression and cognitive scores (MoCA r = -0.118, MMSE r = -0.124; P < 0.05).
  • Lower cognitive scores persisted across all age and educational strata.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69fbf004164b5133a91a427fhttps://doi.org/10.1097/brs.0000000000005717
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Focal compression of the cervical spinal cord alone does not indicate high risk of neurological deterioration in patients with a diagnosis of mild degenerative cervical myelopathy2024 · 7 citations
  2. 2Radiological differences between patients with degenerative cervical myelopathy according to different levels of maximum compression2026
  3. 3E.4 Machine learning based patient classification to predict neurological deterioration in mild Degenerative Cervical Myelopathy2024
  4. 4Advanced MRI metrics improve the prediction of baseline disease severity for individuals with degenerative cervical myelopathy2024 · 8 citations
  5. 5245 Linking Cervical Spinal Cord White Matter Magnetization Transfer Ratio to NIH Toolbox Based Analyses of Motor Function in Degenerative Cervical Myelopathy2024