September 1, 1996Circulation
Arrhythmogenic Right Ventricular Cardiomyopathy
Population
30 hearts with Arrhythmogenic Right Ventricular Cardiomyopathy, age range 15 to 65 years, including 27…
Design
Case_series
Authors
Discussion
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Implication
ARVC fibrofatty pattern was associated with thinner RV wall and myocarditis; hypothesis-generating, requires prospective validation before clinical implications.
Structured PICO
P
Population
30 hearts with Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), age range 15 to 65 years (mean 28 years), including 27 autopsy cases.
C
Comparator
Control hearts (used for comparison of fatty infiltration area)
O
Outcome
Pathological patterns (fatty vs fibrofatty) and ultrastructural characteristics of ARVCsurrogate
ARVC presents with two distinct pathological patterns (fatty and fibrofatty), with the fibrofatty variant characterized by myocardial atrophy likely due to acquired injury and repair mediated by patchy myocarditis.
Cite This Study
Basso et al. (1996) studied this question.