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July 25, 2007European Journal of Cardiovascular Prevention & Rehabilitation

Symptoms of anxiety and depression in patients with stable coronary heart disease: prognostic value and consideration of pathogenetic links

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Why the study?

Do symptoms of anxiety and depression increase the risk of fatal and non-fatal cardiovascular disease events in patients with stable coronary heart disease?

Population

1052 patients with stable coronary heart disease undergoing an in-patient rehabilitation program

Comparison

Symptoms of anxiety and depression vs Patients without manifest or borderline symptoms…

Design

Cohort

Follow-up

3 years

Authors

DRDietrich RothenbacherUniversität UlmHHHarry HahmannPhilipps University of MarburgBWB. WüstenMax Planck Society

Discussion

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Implication

Anxiety symptoms may aid risk stratification in stable CHD; leaves open whether screening or treatment improves outcomes.

Structured PICO

Do symptoms of anxiety and depression increase the risk of fatal and non-fatal cardiovascular disease events in patients with stable coronary heart disease?

P
Population
1052 patients with stable coronary heart disease undergoing an in-patient rehabilitation program
I
Intervention
Symptoms of anxiety and depression (evaluated with the Hospital Anxiety and Depression Scale)
C
Comparator
Patients without manifest or borderline symptoms of anxiety and depression
O
Outcome
Fatal and non-fatal cardiovascular disease eventshard clinical

Manifest anxiety symptoms are significantly associated with an increased risk of fatal and non-fatal cardiovascular events in patients with stable coronary heart disease.

Cite This Study

Rothenbacher et al. (2007) studied this question.

synapsesocial.com/papers/69fc05403a0f4cc134c8ef10https://doi.org/10.1097/hjr.0b013e3280142a02
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Depression as a Risk Factor for Mortality in Patients With Coronary Heart Disease: A Meta-analysis2004 · 1,367 citations
  2. 2Prognostic Association of Depression Following Myocardial Infarction With Mortality and Cardiovascular Events: A Meta-analysis2004 · 1,041 citations
  3. 3The Safety of Tricyclic Antidepressants in Cardiac Patients1993 · 225 citations
  4. 4Inflammation, Depressive Symptomatology, and Coronary Artery Disease2000 · 276 citations