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May 1, 1994CirculationOpen Access

Prospective study of phobic anxiety and risk of coronary heart disease in men.

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Why the study?

Does high phobic anxiety increase the risk of incident coronary heart disease in men without prior cardiovascular disease?

Population

33,999 US male health professionals, aged 42 to 77 years in 1988, who were free of diagnosed cardiovascular…

Comparison

High levels of phobic anxiety vs Lowest levels of anxiety

Design

Cohort

Follow-up

2 years

Authors

Ichiro Kawachi
Ichiro KawachiUniversidade Federal de Minas Gerais
Graham A. Colditz
Graham A. ColditzWashington University in St. Louis
Alberto Ascherio
Alberto AscherioBrigham and Women's Hospital

Discussion

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Implication

High phobic anxiety should not yet prompt screening or intervention in primary prevention; leaves open a causal role in fatal CHD.

Structured PICO

Does high phobic anxiety increase the risk of incident coronary heart disease in men without prior cardiovascular disease?

P
Population
33,999 US male health professionals, aged 42 to 77 years in 1988, who were free of diagnosed cardiovascular disease at baseline
I
Intervention
High levels of phobic anxiety (scoring 4 or higher on the Crown-Crisp index)
C
Comparator
Lowest levels of anxiety (scoring 0 or 1 on the Crown-Crisp index)
O
Outcome
Incidents of coronary heart disease consisting of nonfatal myocardial infarction (MI) and fatal coronary heart disease (CHD)hard clinical

High levels of phobic anxiety are strongly associated with an increased risk of fatal coronary heart disease, particularly sudden death, in men without prior cardiovascular disease.

Cite This Study

Kawachi et al. (1994) studied this question.

synapsesocial.com/papers/69fc05403a0f4cc134c8ef22https://doi.org/10.1161/01.cir.89.5.1992
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