Pulse Entdecken nav.journalClub Debatten Trends Forschende Zeitschriften

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Start Entdecken nav.journalClub Trends

⌘+K

Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers | Synapse

May 7, 2026Proceedings of the National Academy of Sciences0 citationsOpen Access

View Full Paper

Regulation of antiviral and antitumor immunity by the BRCA1 pseudogene in human cancers

YHYoo Jane HanUniversity of Chicago JZJing ZhangUniversity of Chicago MSMaryam ShariffUniversity of Chicago

Key Points

The aim is to explore how the BRCA1 pseudogene influences antiviral and antitumor immunity in various cancers.
Analysis of BRCA1 pseudogene function across different cancer types.
Investigation of the role of pseudogene-derived RNAs in immune regulation.
Targeting pseudogene-derived RNAs shows promise in boosting antitumor responses in breast cancer and other types.
Demonstrates a significant link between BRCA1 pseudogene activity and improved immune defense.

Abstract

in regulating innate immune defense and antitumor responses across cancer types, suggesting that targeting pseudogene-derived RNAs may offer innovative therapeutic strategies to enhance antitumor immunity in breast and other cancers.

KI fragen

Like

Bookmark

Share

View Full Paper

KI fragen

Like

Bookmark

Share

View Full Paper

Cite This Study

Han et al. (Mon,) studied this question.

synapsesocial.com/papers/69fc2c1f8b49bacb8b347c9e https://doi.org/https://doi.org/10.1073/pnas.2528911123