Key result
Alteplase facilitates rescue of an entrapped pericardial pigtail catheter in a 12-year-old with disseminated tuberculosis.
Case report describing the use of alteplase to rescue an entrapped pericardial pigtail catheter in a 12-year-old boy with disseminated tuberculosis.
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Intrapericardial alteplase may avoid surgery for entrapped pigtail catheters in organized TB effusions; leaves open its role pending validation in larger studies.[[1]](https://www.hmpgloballearningnetwork.
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Krishnaswamy et al. (2026) studied this question. Alteplase administration successfully facilitated the rescue of an entrapped pericardial pigtail catheter in a 12-year-old boy with disseminated tuberculosis.
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