Key result
68Ga-DOTATATE PET achieves 100% scan readability for evaluating atherosclerotic inflammation.
Why the study?
Does 68 Ga-DOTATATE PET imaging improve the detection of atherosclerotic inflammation compared to [18F]FDG PET imaging in patients with atherosclerosis?
Observational (n=42)
Does 68 Ga-DOTATATE PET imaging improve the detection of atherosclerotic inflammation compared to [18F]FDG PET imaging in patients with atherosclerosis?
68 Ga-DOTATATE PET imaging is feasible and yields readable scans for assessing atherosclerotic inflammation, potentially overcoming the limitations of [18F]FDG PET.
BACKGROUND: F]FDG lacks cell specificity, and coronary imaging is unreliable because of myocardial spillover. OBJECTIVES: )-binding PET tracer, for imaging atherosclerotic inflammation. METHODS: F]FDG PET imaging in 42 patients with atherosclerosis. RESULTS: Ga-DOTATATE PET scans were readable in all patients. CONCLUSIONS: F]FDG. (Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography [VISION]; NCT02021188).
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Tarkin et al. (2017) conducted an observational in Atherosclerosis (n=42). 68 Ga-DOTATATE PET vs. [18F]FDG PET was evaluated on Readability of PET scans. 68 Ga-DOTATATE PET scans were readable in all 42 patients with atherosclerosis evaluated for atherosclerotic inflammation.
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