Why the study?
Does hemodialysis-induced repetitive myocardial stunning reduce global and regional LV function in patients with HD-induced myocardial ischemia?
Population
30 patients previously identified as developing hemodialysis-induced myocardial ischemia
Comparison
Hemodialysis-induced repetitive myocardial… vs Baseline assessment (within-subject comparison)
Design
Cohort
Follow-up
12 months
Authors
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May link repetitive stunning to systolic decline in HD; hypothesis-generating for targeted interventions before practice change.
Does hemodialysis-induced repetitive myocardial stunning reduce global and regional LV function in patients with HD-induced myocardial ischemia?
Hemodialysis-induced repetitive myocardial stunning over 12 months leads to significant reductions in resting and peak left ventricular ejection fraction, suggesting a mechanism for heart failure development in these patients.
Burton et al. (2009) studied this question.
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