Management of dyslipidaemia in individuals with severe mental illness: a population-based study in the Greater Copenhagen Area

Figures

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  Figure 1.. Study design and patient selection during 2005 and 2015. *Patients without contacts in the Danish Psychiatric Central Register for any mental disorders up to 5 years prior to the index dates and no redeemed prescriptions for antipsychotics, antidepressants, or lithium up to 180 days prior to the index dates. GP, general practitioner; SMI, severe mental illness.

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  Figure 2.. Odds of having lipid biomarker measurements and dyslipidaemia in patients with SMI versus healthy controls without SMI during 2005 and 2015. The logistic regression models were adjusted for age, gender and the somatic comorbidities listed in Table 1 and educational position. Information regarding number of persons contributing to the analyses, biochemical thresholds for elevated/low lipid parameters and odds of having measured the individual lipid profile parameters is available in Supplemental Table S7. *Defined as individuals with elevated LDL-C, elevated triglycerides, or low HDL-C. C, Cholesterol; CI, confidence interval; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OR, odds ratio; SMI, severe mental illness; TG, triglycerides.

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  Figure 3.. Odds of redeeming prescriptions on lipid-lowering pharmacotherapy in patients with SMI versus healthy controls without SMI during 2005 and 2015. The logistic regression models were adjusted for age, gender and educational position. Subgroups are defined as persons with previous hospital contacts for the individual diseases up to 5 years before January 1st in 2005 and 2015, respectively. Information regarding number of persons contributing to the analyses is available in Supplemental Table S11. ACS, acute coronary syndrome; CKD, chronic kidney disease; CI, confidence interval; IHD, ischaemic heart disease; OR, odds ratio; PAD, peripheral artery disease; SMI, severe mental illness; Stroke/TIA, ischaemic stroke or transient ischaemic attack.