Key result
Patients with severe mental illness and comorbid coronary heart disease or heart failure were significantly less likely to be prescribed beta blockers (OR 0.48) and ACEI/ARBs (OR 0.42) compared to those without severe mental illness.
Why the study?
Does severe mental illness reduce the likelihood of receiving guideline-directed medical therapy for cardiovascular disease?
Cross-Sectional (n=274,725)
Does severe mental illness reduce the likelihood of receiving guideline-directed medical therapy for cardiovascular disease?
Odds Ratio: 0.48 (95% CI 0.33–0.69)
Absolute Event Rate: 52.7% vs 68.3%
p-value: p=<0.001
Patients with severe mental illness and comorbid coronary heart disease or heart failure are significantly less likely to be prescribed guideline-directed beta blockers and ACEI/ARBs compared to those without severe mental illness.
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May signal care gaps in severe mental illness; observational data leaves open causality and needs prospective confirmation.
Woodhead et al. (2016) conducted a cross-sectional in Severe mental illness and cardiovascular disease (n=274,725). Severe mental illness vs. No severe mental illness was evaluated on Beta blocker prescribing among patients with coronary heart disease or heart failure (OR 0.48, 95% CI 0.33-0.69, p=<0.001). Patients with severe mental illness and comorbid coronary heart disease or heart failure were significantly less likely to be prescribed beta blockers (OR 0.48) and ACEI/ARBs (OR 0.42) compared to those without severe mental illness.
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