Why the study?
Does the expression of adipokines in periaortic and epicardial adipose tissue correlate with aortic and coronary atherosclerosis?
Population
Human periaortic, pericoronary and apical epicardial adipose tissue samples
Design
Cross-sectional
Authors
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Hypothesis-generating for site-specific adipokine roles in atherosclerosis; should not change practice without prospective validation.
Does the expression of adipokines in periaortic and epicardial adipose tissue correlate with aortic and coronary atherosclerosis?
Locally produced adipokines in periaortic and epicardial adipose tissue show distinct expression patterns that correlate differently with aortic and coronary atherosclerosis, suggesting location-specific roles in the atherosclerotic process.
Spiroglou et al. (2010) studied this question.
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