Significance of left ventricular outflow tract cross-sectional area in hypertrophic cardiomyopathy: a two-dimensional echocardiographic assessment.
Why the study?
Does left ventricular outflow tract cross-sectional area correlate with the presence of subaortic obstruction in patients with hypertrophic cardiomyopathy?
Population
81 subjects total: 65 patients with hypertrophic cardiomyopathy and 16 normal controls.
Comparison
Measurement of left ventricular outflow tract… vs Normal controls and internal comparison between…
Design
Cross-sectional
Authors
Discussion
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Implication
May aid obstruction assessment via LVOT area in HCM; confirms association but leaves open prognostic utility.
Structured PICO
Does left ventricular outflow tract cross-sectional area correlate with the presence of subaortic obstruction in patients with hypertrophic cardiomyopathy?
P
Population
81 subjects total: 65 patients with hypertrophic cardiomyopathy and 16 normal controls.
I
Intervention
Measurement of left ventricular outflow tract (LVOT) cross-sectional area by quantitative two-dimensional echocardiography.
C
Comparator
Normal controls and internal comparison between hypertrophic cardiomyopathy patients with versus without subaortic obstruction.
O
Outcome
Left ventricular outflow tract (LVOT) cross-sectional area and its relation to the presence or absence of subaortic obstruction.surrogate
A smaller left ventricular outflow tract cross-sectional area measured by 2D echocardiography is strongly associated with the presence of subaortic obstruction in patients with hypertrophic cardiomyopathy.
Cite This Study
Spirito et al. (1983) studied this question.