Prognostic Value of Noninvasive Cardiovascular Testing in Patients With Stable Chest Pain
Why the study?
Does coronary computed tomography angiography (CTA) improve prognostic information compared to functional testing in patients with stable chest pain and intermediate pretest probability for obstructive CAD?
Population
Patients with stable chest pain and intermediate pretest probability for obstructive coronary artery disease
Comparison
Coronary computed tomography angiography (CTA) vs Functional testing
Design
RCT, randomly assigned
Follow-up
median 26.1 months
Authors
Discussion
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Member takes
Implication
Reclassifying normal functional tests as mildly abnormal improves discrimination; extends CTA's prognostic value over functional testing in stable chest pain.
Structured PICO
Does coronary computed tomography angiography (CTA) improve prognostic information compared to functional testing in patients with stable chest pain and intermediate pretest probability for obstructive CAD?
P
Population
Patients with stable chest pain and intermediate pretest probability for obstructive coronary artery disease (CAD)
I
Intervention
Coronary computed tomography angiography (CTA)
C
Comparator
Functional testing (exercise electrocardiography, nuclear stress, or stress echocardiography)
O
Outcome
Composite of death, myocardial infarction, or unstable angina hospitalizations over a median follow-up of 26.1 monthscomposite
Coronary CTA provides better prognostic information than functional testing in patients with stable chest pain by identifying those at risk due to nonobstructive CAD.
Cite This Study
Hoffmann et al. (2017) studied this question.