Why the study?
The role of obesity as a coronary heart disease risk factor in nondiabetic, normotensive individuals was less well established.
What is the relationship between obesity, insulin resistance, and coronary heart disease risk factors in nondiabetic, normotensive healthy individuals?
Population
314 nondiabetic, normotensive, healthy volunteers
Comparison
Relationships between BMI, insulin resistance, and nine CHD risk factors
Authors
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Extends obesity as CHD risk factor to normotensive nondiabetics; leaves open whether reducing insulin resistance improves outcomes.**[[1]](https://www.jacc.org/doi/abs/10.1016/s0735-1097%2802%2902051-x)[[2]](https://pubmed.ncbi.nlm.nih.
What is the relationship between obesity, insulin resistance, and coronary heart disease risk factors in nondiabetic, normotensive healthy individuals?
In healthy, normotensive, nondiabetic individuals, both obesity and insulin resistance independently predict coronary heart disease risk factors.
Abbasi et al. (2002) studied this question.
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