Why the study?
Understanding of factors predisposing SCAD patients to worse outcomes, such as concurrent sudden cardiac arrest and secondary prevention of sudden cardiac death, is limited.
While SCAD with concurrent cardiac arrest is associated with worse outcomes, the long-term rate of administered defibrillator therapies is low, supporting a conservative approach to device implantation.
Answers are grounded in this paper and cite their sources.
Low therapy rates may support conservative ICD/WCD use in SCAD arrest survivors; extends limited evidence on arrhythmia burden.
Background: Our understanding of factors predisposing patients with spontaneous coronary artery dissection (SCAD) to worse outcomes, such as concurrent sudden cardiac arrest (CA) and secondary prevention of sudden cardiac death in those patients, is limited. Objective: We conducted the largest systematic review of studies assessing clinical outcomes in SCAD with concurrent CA. Methods: This study was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane, and Scopus were searched using relevant search terms including "Spontaneous Coronary Artery Dissection," "Ventricular Tachycardia," "Ventricular Fibrillation," "Sudden Cardiac Death," and "Cardiac Arrest." The search was conducted from database inception to January 2025. Out of a pooled 35 implanted cardiac defibrillators (ICDs) and wearable cardiac defibrillators (WCDs), there was only 1 appropriate and 1 inappropriate defibrillator discharge recorded over the follow-up period. Conclusion: SCAD with concurrent CA is associated with worse in-hospital and long-term outcomes, although long-term rate of administered defibrillator therapies was low, supporting a conservative approach.
No takes yet. Share an insight, caveat, or question.
Baqal et al. (2025) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: