April 20, 1999Circulation

Determinants and Prognostic Implications of Persistent ST-Segment Elevation After Primary Angioplasty for Acute Myocardial Infarction

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Why the study?

Does persistent ST-segment elevation after successful PTCA predict worse clinical outcomes in patients with acute myocardial infarction?

Population

91 patients with acute myocardial infarction (AMI) after successful primary angioplasty (PTCA)

Comparison

Impaired microvascular reperfusion vs Preserved microvascular reperfusion

Design

Cohort

Follow-up

1-year

Authors

MCMarc J. ClaeysInterventional Cardiology JBJohan BosmansUniversity of Antwerp LVLeonard VeenstraAntwerp University Hospital

Discussion

Member takes

Implication

Persistent ST elevation post-PCI may flag high-risk AMI patients for closer surveillance; leaves open whether microvascular therapies reduce MACE.

Structured PICO

Does persistent ST-segment elevation after successful PTCA predict worse clinical outcomes in patients with acute myocardial infarction?

Population

91 patients with acute myocardial infarction (AMI) after successful primary angioplasty (PTCA)

Intervention

Impaired microvascular reperfusion (persistent ST-segment elevation ≥50% of initial value at the end of coronary intervention)

Comparator

Preserved microvascular reperfusion (ST-segment elevation <50%)

Outcome

Clinical outcome at 1-year follow-up including cardiac death, nonfatal MI, and total major adverse cardiac events (MACE)hard clinical

Persistent ST-segment elevation after successful primary angioplasty for AMI is a strong independent predictor of major adverse cardiac events at 1 year, highlighting the clinical impact of microvascular reperfusion injury.

Cite This Study

Claeys et al. (1999) studied this question.

synapsesocial.com/papers/69fd568e5c6eda2188019257 https://doi.org/10.1161/01.cir.99.15.1972

Topics

Heart failure HFrEF treatment

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Implication

Persistent ST elevation post-PCI may flag high-risk AMI patients for closer surveillance; leaves open whether microvascular therapies reduce MACE.

Determinants and Prognostic Implications of Persistent ST-Segment Elevation After Primary Angioplasty for Acute Myocardial Infarction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Determinants and Prognostic Implications of Persistent ST-Segment Elevation After Primary Angioplasty for Acute Myocardial Infarction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider