May 8, 2026Journal of Materials Science Research and Reviews0 citations
Effect of Free and Nanoparticle-Based Vitamin C and Curcumin on Renal Function, Lipid Profile, and Kidney Histology in Adenine-induced Chronic Kidney Disease in Male Wistar Rats
This research aims to determine how free and nanoparticle-based vitamin C and curcumin affect kidney function, lipid levels, and kidney tissue in a chronic kidney disease model.
Used adenine-induced chronic kidney disease model in male Wistar rats.
Administered free and nanoparticle formulations of vitamin C and curcumin.
Evaluated renal function, lipid profile, and kidney histology post-treatment.
Vitamin C and curcumin improved renal function markers significantly (p<0.05).
Lipid profiles showed a reduction in harmful cholesterol levels in treated groups (p<0.01).
Histological analysis indicated better kidney structure and reduced damage in treated rats compared to control.