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May 8, 2026Annals of Nutrition and Metabolism

Human Milk Bioactives in Breastfeeding: Understanding the Complex Biology of Mother-Child Interactions

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Authors

APAndrew M. PrenticeMRC Unit the Gambia

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Overview

This supplement explores the role of human milk bioactives in immune development and the challenges of breastfeeding.

Key Points

  • The papers examine the biological interplay of human milk bioactives on immune and nutritional outcomes in infants.
  • Reviewed literature on human milk composition across diverse populations
  • Analyzed longitudinal data from the MILQ study
  • Discussed immune mechanisms and responses linked to breastfeeding.
  • Milk composition varies based on maternal nutrition but supports adequate infant needs.
  • Human milk bioactives strengthen the infant's immune system and gut barrier.
  • Iron levels in human milk are low, necessitating supplementation for at-risk infants.

Cite This Study

Andrew M. Prentice (2026) studied this question.

synapsesocial.com/papers/69fd7ddcbfa21ec5bbf06112https://doi.org/10.1159/000551893
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human milk bioactive compounds and allergic and infectious immunological outcomes: A systematic review2025
  2. 2The Benefits of Human Breast Milk in Neonates and Infants: A Narrative Review2026
  3. 3Breastmilk and immune function2026 · 2 citations
  4. 4Human Milk Oligosaccharides Support Coordinated Microbiome and Immune Development and Function in Infancy2026 · 2 citations
  5. 5Human Milk Oligosaccharides: Potential Upshot on Health at Early Life Stage Development2024 · 4 citations