Recalcitrant tinea infections due to Trichophyton indotineae in the United States (2025–2026): a retrospective case series identified by real-time PCR

is an emerging dermatophytic pathogen causing severe infections that are frequently resistant to standard antifungals. Since 2015, this species has spread intercontinentally. OBJECTIVES: infections in the United States and to introduce the utility of rapid real-time PCR (qPCR) diagnosis. METHODS: ) was sequenced to assess terbinafine resistance. A survey was distributed to treating physicians to collect information on recent international travel, household transmission, clinical features, immunosuppressive medications or conditions, and treatment history. RESULTS AND CONCLUSIONS: cases, these practices may increase the risk of disease recurrence and domestic spread. Current clinical recommendations are summarized herein, highlighting the utility of this novel qPCR assay for real-time treatment decision-making.