Why the study?
The incidence of sudden cardiac death and arrhythmic sudden death, as determined by autopsy, in persons with HIV infection had not been clearly established.
Does HIV infection increase the incidence of sudden cardiac death and sudden death caused by arrhythmia in persons 18 to 90 years of age?
Population
Persons 18 to 90 years of age with out-of-hospital cardiac arrest death, with or without known HIV infection
Comparison
Persons with known HIV infection vs persons without known HIV infection
Design
Prospective postmortem cohort study
Authors
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HIV infection was associated with higher presumed sudden cardiac death rates; leaves open arrhythmia-specific risk after accounting for overdose.
Does HIV infection increase the incidence of sudden cardiac death and sudden death caused by arrhythmia in persons 18 to 90 years of age?
HIV infection is associated with a more than twofold higher incidence of presumed sudden cardiac death, though one third of these deaths are attributable to occult drug overdose.
Tseng et al. (2021) studied this question.
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