Randomized trial evaluates clinical severity in acute intracerebral hemorrhage, indicating higher MMP-9 levels relate to worse outcomes.
Key Points
This study aims to assess the relationship between clinical severity of acute intracerebral hemorrhage, as measured by the NIHSS, and plasma MMP-9 levels.
Included 50 patients with acute intracerebral hemorrhage.
Patients assessed using the NIHSS to categorize severity.
Plasma MMP-9 levels were measured and analyzed statistically.
Majority of patients had moderate to very severe neurological deficits, with average NIHSS score of 16.
Elevated plasma MMP-9 levels were observed across all severity groups, increasing with NIHSS scores.
Strong positive correlation between MMP-9 concentration and clinical severity (p < 0.001).