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May 8, 2026European Stroke JournalOpen Access

Abstract Number: Esoc2026a217 Hypoperfusion Intensity Ratio May Not Be a Good Predictor of Functional Outcome in Anterior Circulation Large Vessel Occlusion Stroke When Adjusting for Multiple Covariates

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Authors

AKAmeya KaleSRSrinath RamananPJPooja Jethwani

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Overview

Retrospective analysis examines the predictive value of hypoperfusion ratio in anterior circulation large vessel occlusion stroke, suggesting alternative predictors.

Key Points

  • This study aims to evaluate the predictive ability of hypoperfusion intensity ratio for functional outcomes in large vessel occlusion stroke while adjusting for covariates.
  • Single center retrospective study analyzing clinical data from electronic medical records.
  • Multivariate logistic regression was performed on 83 patients to assess the association of hypoperfusion intensity ratio with 90-day mRS outcomes.
  • Comparison of variables using Mann-Whitney U, Chi-squared, and independent t-tests.
  • Of the 83 records analyzed, 65% underwent endovascular therapy (EVT), with 49% achieving a modified Rankin Scale (mRS) score of ≤2 at 90 days.
  • Good functional outcomes correlated with lower prior stroke rates (7.3% vs. 3.8%, p=0.039) and higher ASPECTS scores (median 8 vs. 7, p=0.004).
  • Higher Tmax > 6s was identified as a predictor of 90-day functional independence (OR 1.03; p=0.026).

Cite This Study

Kale et al. (2026) studied this question.

synapsesocial.com/papers/69fd7ee0bfa21ec5bbf073a3https://doi.org/10.1093/esj/aakag023.1253
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