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May 8, 2026Journal of Cosmetic DermatologyOpen Access

Efficacy and Safety of Non‐Cross‐Linked Hyaluronic Acid Mesotherapy for Post‐Acne Erythema: A Split‐Face, Prospective, Randomized, Single‐Center Trial

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Authors

DZDi ZhangCapital Medical UniversityYCYUAN CHANGMinistry of Health and WelfareYBYue BaiCapital Medical University

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Implication

Randomized trial evaluates efficacy of hyaluronic acid mesotherapy for post-acne erythema, suggesting potential benefits in skin recovery.

Key Points

  • This trial aims to assess the efficacy and safety of non-cross-linked hyaluronic acid mesotherapy for treating post-acne erythema.
  • Conducted at a single center with 25 patients aged 18-35 years.
  • Three treatment sessions at 4-week intervals were administered.
  • Primary outcome measured was the Clinician Erythema Assessment Scale at baseline and week 12.
  • At week 12, the mesotherapy group had significantly lower CEAS scores than the control group.
  • Improvements in skin parameters (red areas, pores, texture) were more prominent in the mesotherapy group.
  • No serious adverse events occurred, with only one patient experiencing acne relapse.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69fd7f25bfa21ec5bbf078ddhttps://doi.org/10.1111/jocd.70813
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