Key result
Elevated LAVI in STEMI linked to a ~111% increase in in-hospital arrhythmias.
Why the study?
Prospective data assessing in-hospital clinical outcomes using left atrial volume index in Indian patients with STEMI were lacking.
Does an elevated left atrial volume index (≥32 mL/m²) predict worse in-hospital outcomes and complications in patients with ST-elevation myocardial infarction?
Observational (n=110)
Does an elevated left atrial volume index (≥32 mL/m²) predict worse in-hospital outcomes and complications in patients with ST-elevation myocardial infarction?
Absolute Event Rate: 63.3% vs 30%
Elevated left atrial volume index (≥32 mL/m²) measured within 24-72 hours of admission is a simple, noninvasive predictor of higher in-hospital complications, including arrhythmias, in STEMI patients.
Hypothesis-generating for elevated LAVI and in-hospital arrhythmia risk; prospective validation needed before clinical adoption.
Export Objective: The objective of the study was to evaluate the association between left atrial volume index (LAVI) and in-hospital outcomes in patients with ST-elevation myocardial infarction (STEMI). This is the first prospective Indian study assessing in-hospital clinical outcomes using LAVI. Materials and Methods: This prospective observational study included consecutive STEMI patients who underwent transthoracic echocardiography within 24–72 h of admission. Patients were stratified by LAVI <32 mL/m² and ≥32 mL/m². Baseline characteristics, echocardiographic parameters, and in-hospital adverse events were compared between groups. Results: Of 110 STEMI patients, 80 had LAVI <32 mL/m² and 30 had LAVI ≥32 mL/m². Patients with higher LAVI had lower ejection fraction, higher E/e′ ratio, higher wall motion score index, and more frequent Killip class ≥2 at presentation. In-hospital complications, particularly arrhythmias (63.3% vs. 30.0%) and left ventricular systolic dysfunction, were more common in the LAVI ≥32 mL/m² group. Conclusion: Elevated LAVI is a simple, noninvasive, and easily reproducible echocardiographic marker associated with worse functional parameters and higher in-hospital complication rates. Incorporating LAVI into early risk stratification may facilitate timely identification of high-risk STEMI patients.
No takes yet. Share an insight, caveat, or question.
Thota et al. (2026) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=110). LAVI ≥32 mL/m² vs. LAVI <32 mL/m² was evaluated on In-hospital arrhythmias. Elevated left atrial volume index (≥32 mL/m²) in STEMI patients was associated with a higher rate of in-hospital arrhythmias compared to those with LAVI <32 mL/m² (63.3% vs. 30.0%).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: