Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 8, 2026European Stroke Journal

Abstract Number: Esoc2026a852 Bypassing Primary Stroke Centres for Thrombectomy-Capable Centres Improves Functional Outcomes: A Systematic Review and Meta-Analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

TIThies IngwersenPEPatrick EderRBRafael Bourry

Discussion

Loading...

Member takes

Overview

Systematic review shows pre-hospital bypass to thrombectomy centres improves outcomes in stroke patients, highlighting the need for new protocols.

Key Points

  • This research investigates whether direct transport to thrombectomy-capable centres improves functional outcomes in stroke patients compared to the nearest primary stroke centres.
  • Systematic review registered with PROSPERO, adhering to PRISMA guidelines.
  • Searched PubMed and Web of Science for studies on transport to stroke centres versus thrombectomy-capable centres.
  • Included randomised and non-randomised studies reporting functional outcomes, with a meta-analysis applied.
  • Bypassing strategies led to higher EVT rates (OR 1.69, 95% CI 1.22 – 2.34) and a reduction in time-to-groin-puncture (-50.74 min, 95% CI -69.86 – -31.61).
  • IVT rates showed no significant difference (OR 1.14, 95% CI 0.93 – 1.40).
  • Functional independence at 90 days was significantly higher for bypass patients (mRS 0 – 2: OR 1.23, 95% CI 1.07 – 1.41) and severe disability or death was less frequent (OR 0.81, 95% CI 0.67 – 0.98).

Cite This Study

Ingwersen et al. (2026) studied this question.

synapsesocial.com/papers/69fd7fb8bfa21ec5bbf0838fhttps://doi.org/10.1093/esj/aakag023.448
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ABSTRACT NUMBER: ESOC2026A1329 TIME TO ENDOVASCULAR TREATMENT IN MEDIUM OR DISTAL VESSEL OCCLUSION STROKE: A SECONDARY ANALYSIS OF THE DISTAL TRIAL2026
  2. 2ABSTRACT NUMBER: ESOC2026A670 PERFUSION IMAGING AND CLINICAL OUTCOME IN ACUTE STROKE WITH POSTERIOR CEREBRAL ARTERY OCCLUSION2026
  3. 3ABSTRACT NUMBER: ESOC2026A2480 INFARCT IN NEW TERRITORY AFTER ENDOVASCULAR TREATMENT: AN INDIVIDUAL PARTICIPANT DATA META-ANALYSIS OF RANDOMIZED TRIALS COMPARING INTRAVENOUS THROMBOLYSIS PLUS EVT VERSUS EVT ALONE2026
  4. 4ABSTRACT NUMBER: ESOC2026A1252 INTRAVENOUS THROMBOLYSIS IN ACUTE ISCHEMIC STROKE PATIENTS ON DIRECT ORAL ANTICOAGULANTS UNDERGOING ENDOVASCULAR THROMBECTOMY2026
  5. 5ABSTRACT NUMBER: ESOC2026A1408 INTRAVENOUS TENECTEPLASE FOR LARGE-VESSEL OCCLUSION: META-ANALYSIS OF OUTCOMES WITH AND WITHOUT ACCESS TO THROMBECTOMY2026