Retrospective analysis identifies predictors of successful reperfusion in distal medium vessel occlusions, suggesting implications for treatment strategies.
Key Points
This study aims to evaluate predictors and clinical outcomes of first-pass reperfusion in patients with distal-medium vessel occlusions treated with endovascular therapy.
Retrospective analysis of DMVO-AIS patients treated at a comprehensive stroke centre from May 2016 to March 2025.
Used univariate and multivariable logistic regression to identify predictors and outcomes associated with first-pass reperfusion.
Among 658 patients, FPR achieved in 50.5% of cases, with aspiration as the first technique used in 97.4%.
Shorter onset-to-puncture time and aspiration as first technique were independent predictors of FPR (OR=4.06, p=0.035; OR=1.02 per 30-minute reduction, p=0.047).
90-day mRS 0-2 was achieved in 43.8% of patients, with FPR associated with lower NIHSS at 24 hours (p<0.001) and lower mRS at 90 days (p<0.001).