Key result
Greater relative handgrip strength linked to lower large artery stiffness in women after middle age.
Why the study?
Is relative handgrip strength associated with large artery stiffness in women across the lifespan?
Observational
Is relative handgrip strength associated with large artery stiffness in women across the lifespan?
Muscular strength, as measured by handgrip strength, is associated with lower large artery stiffness specifically in older women, suggesting its importance for vascular health following midlife.
Should not yet change vascular risk assessment using handgrip strength in women; leaves open age-dependent associations and benefits of strength training.
The present study investigated the association between relative handgrip strength and large artery stiffness in women across the lifespan. Greater relative handgrip strength was not associated with large artery stiffness in young or middle-aged women but was associated with lower large artery stiffness in older women. This age-moderating effect suggests the impact of muscular strength on large artery stiffness changes across the lifespan and becomes more important for vascular health in women following midlife.
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Mascone et al. (2026) reported an observational. Relative handgrip strength was evaluated on Large artery stiffness. Greater relative handgrip strength was associated with lower large artery stiffness in older women, but not in young or middle-aged women.
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