Why the study?
Does clopidogrel plus aspirin reduce the composite of myocardial infarction or death from cardiac causes compared to aspirin alone in patients who received drug-eluting stents and were event-free for 12 months?
Does clopidogrel plus aspirin reduce the composite of myocardial infarction or death from cardiac causes compared to aspirin alone in patients who received drug-eluting stents and were event-free for 12 months?
Extending dual antiplatelet therapy beyond 12 months after drug-eluting stent implantation did not significantly reduce ischemic events compared to aspirin monotherapy.
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Supports limiting DAPT to 12 months post-DES; confirms no ischemic benefit from extension in event-free patients.
Park et al. (2010) studied this question.
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