Population
56 subjects: 14 healthy normotensive volunteers and 42 hypertensive patients
Design
Cross-sectional
Authors
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Supports aldosterone/endothelin association with myocardial texture changes in hypertension; leaves open causal role and clinical relevance.
Circulating aldosterone and endothelin levels correlate with myocardial integrated backscatter, suggesting they may induce alterations in left ventricular myocardial texture and collagen content in hypertensive patients.
Kozàkovà et al. (2003) studied this question.
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