Why the study?
Does plasma aldosterone correlate with systemic arterial compliance in patients with essential hypertension?
Population
92 subjects, including 56 patients with sustained essential hypertension and 36 normotensive controls.
Comparison
Measurement of systemic arterial compliance and… vs Normotensive controls.
Design
Cross-sectional
Authors
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Supports aldosterone's link to reduced arterial compliance in hypertension; hypothesis-generating, needs prospective trials before practice change.
Does plasma aldosterone correlate with systemic arterial compliance in patients with essential hypertension?
Plasma aldosterone levels are negatively correlated with systemic arterial compliance in essential hypertension, suggesting aldosterone modulates arterial function.
Jacques Blacher (1997) studied this question.
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