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June 1, 2000Journal of Biological ChemistryOpen Access

Controlled Protein Degradation Regulates Ribonucleotide Reductase Activity in Proliferating Mammalian Cells during the Normal Cell Cycle and in Response to DNA Damage and Replication Blocks

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Authors

ACAndrei ChabesUmeå UniversityLTLars ThelanderUniversité Paris-Sud

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Chabes et al. (2000) studied this question.

synapsesocial.com/papers/69fe8782b124fe581985167dhttps://doi.org/10.1074/jbc.m000799200
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Also Consider

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  1. 1S-Phase-specific expression of mammalian ribonucleotide reductase R1 and R2 subunit mRNAs1990 · 178 citations
  2. 2Coordinate overproduction of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in hamster cells resistant to pyrazofurin and 6-azauridine.1979 · 66 citations
  3. 3Phosphorylation of ribonucleotide reductase R2 protein: In vivo and in vitro evidence of a role for p34cdc2 and CDK2 protein kinases1993 · 27 citations
  4. 4Elevated expression of M1 and M2 components and drug-induced posttranscriptional modulation of ribonucleotide reductase in a hydroxyurea-resistant mouse cell line1987 · 49 citations
  5. 5INTERACTIONS BETWEEN DEOXYRIBONUCLEOTIDE AND DNA SYNTHESIS1988 · 778 citations