August 15, 1996Circulation
Remote Noninfarcted Region Dysfunction Soon After First Anterior Myocardial Infarction
Why the study?
Does magnetic resonance myocardial tagging demonstrate reduced function in remote noninfarcted regions early after anterior MI compared to normal subjects?
Population
28 patients studied on day 5 +/- 2 after first anterior MI, with single-vessel LAD disease, reperfusion…
Comparison
Magnetic resonance (MR) myocardial tagging vs Normal control subjects
Design
Cross-sectional
Follow-up
Day 5 +/- 2 after MI
Authors
Discussion
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Member takes
Implication
Reduced remote myocardial shortening early after anterior MI; extends evidence of global LV impairment but leaves clinical relevance open.
Structured PICO
Does magnetic resonance myocardial tagging demonstrate reduced function in remote noninfarcted regions early after anterior MI compared to normal subjects?
P
Population
28 patients (25 male; mean age, 52 years) studied on day 5 +/- 2 after first anterior MI, with single-vessel LAD disease, reperfusion therapy, regional LV dysfunction, and EF <= 50%, and 10 normal control subjects (7 male; mean age, 43 years).
I
Intervention
Magnetic resonance (MR) myocardial tagging
C
Comparator
Normal control subjects
O
Outcome
Percent circumferential shortening (%S) on a topographic basissurrogate
MR myocardial tagging demonstrates that patients early after a first anterior MI have reduced intramyocardial circumferential shortening throughout the left ventricle, including in remote noninfarcted regions.
Cite This Study
Kramer et al. (1996) studied this question.