August 1, 1981Circulation
Impaired left ventricular diastolic filling in patients with coronary artery disease: assessment with radionuclide angiography.
Why the study?
Does radionuclide angiography detect abnormal left ventricular diastolic filling at rest in patients with coronary artery disease?
Population
231 patients with coronary artery disease (CAD)
Comparison
Radionuclide angiography to assess left… vs Normal mean values
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Radionuclide angiography may identify resting diastolic abnormalities in CAD; leaves open its diagnostic role pending prospective validation.
Structured PICO
Does radionuclide angiography detect abnormal left ventricular diastolic filling at rest in patients with coronary artery disease?
P
Population
231 patients with coronary artery disease (CAD)
I
Intervention
Radionuclide angiography to assess left ventricular (LV) diastolic filling at rest
C
Comparator
Normal mean values
O
Outcome
Peak LV filling rate (PFR) and time to PFR (TPFR)surrogate
Radionuclide angiography demonstrates that LV diastolic filling is abnormal in a high percentage of CAD patients at rest, independent of LV systolic function or previous MI.
Cite This Study
Bonow et al. (1981) studied this question.