Why the study?
Does coronary CT angiography (CCTA) improve prediction of all-cause mortality and non-fatal myocardial infarction over the Framingham risk score and coronary artery calcium score in asymptomatic individuals without known CAD?
Does coronary CT angiography (CCTA) improve prediction of all-cause mortality and non-fatal myocardial infarction over the Framingham risk score and coronary artery calcium score in asymptomatic individuals without known CAD?
Coronary CT angiography provides incremental prognostic utility for predicting mortality and non-fatal MI in asymptomatic individuals with moderately high coronary artery calcium scores (101-400), but not for those with lower or higher scores.
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CCTA should not yet alter risk stratification in asymptomatic patients; leaves open targeted use when CACS >100 pending prospective validation.
Cho et al. (2014) studied this question.
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