May 25, 1999Circulation
Coronary Calcium Does Not Accurately Predict Near-Term Future Coronary Events in High-Risk Adults
Why the study?
Does EBCT coronary calcium score improve the prediction of near-term future coronary events compared to traditional risk-factor assessment in asymptomatic high-risk adults?
Population
1196 asymptomatic high-coronary-risk adults with multiple coronary risk factors, mean age 66 years.
Comparison
Cardiac electron-beam CT scanning for coronary… vs Risk-factor assessment
Design
Cohort
Follow-up
41 months
Authors
Discussion
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Member takes
Implication
Does not support routine coronary calcium scoring for near-term risk stratification in high-risk asymptomatic adults; leaves open its value in other populations.
Structured PICO
Does EBCT coronary calcium score improve the prediction of near-term future coronary events compared to traditional risk-factor assessment in asymptomatic high-risk adults?
P
Population
1196 asymptomatic high-coronary-risk adults with multiple coronary risk factors, mean age 66 years.
I
Intervention
Cardiac electron-beam CT (EBCT) scanning for coronary calcium score
C
Comparator
Risk-factor assessment (Framingham model and data-derived risk model)
O
Outcome
Coronary events (coronary death or nonfatal infarction) at 41 months follow-uphard clinical
EBCT coronary calcium score does not accurately predict near-term coronary events or add significant incremental prognostic information to traditional risk factors in asymptomatic high-risk adults.
Cite This Study
Detrano et al. (1999) studied this question.