> 0.99). Analytes were stable for 96 hours at -20°C and yielded consistent qualitative results after >400 days of storage. No cross-reactivity was observed between hrHPV types or low-risk types (HPV6, HPV11). These results support the use of MyHPVscore as an LDT for detecting HPV+ oropharynx cancer. This methodology establishes an approach and standard controls that can benchmark other emerging ctDNA assays.
Currie et al. (Fri,) studied this question.