Risk, prevalence and survival outcomes of ovarian cancer in women with endometriosis: the ENDOCANCER systematic review and meta-analysis

Ilaria Piacenti; Veronica Tius; Benedetta Gomba; Stefano Restaino; Martina Arcieri; Silvia Zermano; Anna Biasioli; Federica Perelli; Diego RAIMONDO; Lucia Lazzeri; Alberto Mattei; Errico Zupi; Renato SERACCHIOLI; Giuseppe Vizzielli

doi:10.1016/j.jmig.2026.04.021

May 1, 2026Journal of Minimally Invasive GynecologyOpen Access

Risk, prevalence and survival outcomes of ovarian cancer in women with endometriosis: the ENDOCANCER systematic review and meta-analysis

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Key Points

This research aims to analyze the relationship between endometriosis and the risk of developing epithelial ovarian cancer, along with survival outcomes.
Systematic review and meta-analysis of existing studies on ovarian cancer and endometriosis.
Focus on risk factors, histotype distribution, and prognostic outcomes.
Data compiled from multiple sources to establish a clearer link.
Increased risk of clear cell and endometrioid subtypes of ovarian cancer in women with endometriosis.
Survival outcomes vary significantly based on histotype distribution.
Evidence supports a notable connection between endometriosis and epithelial ovarian cancer.

Implication

Systematic review examines ovarian cancer risk and survival in women with endometriosis, indicating important health implications.

Abstract

OBJECTIVE:Endometriosis is linked to an increased risk of epithelial ovarian cancer (EOC), especially clear cell and endometrioid subtypes.The extent and prognostic significance of this link are still not fully understood.This systematic review and meta-analysis compiles existing evidence on ovarian cancer risk, histotype distribution, and survival outcomes in women with endometriosis.

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Cite This Study

Piacenti et al. (2026) studied this question.

synapsesocial.com/papers/69fecf49b9154b0b828763b4 https://doi.org/10.1016/j.jmig.2026.04.021

View Full Paper

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Risk, prevalence and survival outcomes of ovarian cancer in women with endometriosis: the ENDOCANCER systematic review and meta-analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

Risk, prevalence and survival outcomes of ovarian cancer in women with endometriosis: the ENDOCANCER systematic review and meta-analysis

Key Points

Implication

Abstract

Discussion

Cite This Study

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