Metal-Free, Iodine/DMSO-Promoted Oxidative C(sp 2 )-H Difunctionalization: Synthesis of Aminochalcogenylated Indoles

Key Points

• This research aims to establish a metal-free method for the oxidative difunctionalization of indole compounds.
• Utilized iodine and DMSO as primary reagents for the process.
• Developed a protocol that is environmentally friendly and efficient.
• Successful synthesis of aminochalcogenylated indoles without metal catalysts.
• Demonstrated improved efficiency in creating complex indole derivatives.