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The aim is to optimize the alkali-ethanol fractionation process of Miscanthus × giganteus for sustainable production.

May 9, 2026Open Access

Optimization of alkali-ethanol fractionation of Miscanthus using response surface methodology

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The aim is to optimize the alkali-ethanol fractionation process of Miscanthus × giganteus for sustainable production.
Used Box-Behnken Design (BBD) to screen four independent variables at low severity.
Employed Central Composite Design (CCD) to optimize temperature and alkali concentration at high severity.
Conducted chemical and morphological analyses to confirm results.
In low severity, optimal polysaccharide yield achieved 73.3% with 96.9% cellulose retention, 92.2% xylan retention; 83.1% lignin removal for delignification.
In high severity, polysaccharide yield resulted in 88.2% cellulose and 67.6% xylan retention, with 91.3% lignin removal for delignification.

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Randomized trial optimizes pulp yield and delignification in Miscanthus, indicating a pathway for sustainable biorefineries.

Choo et al. (2026) studied this question.

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