What question did this study set out to answer?

This study aims to identify predictors and outcomes of cryptococcal infections in liver transplant recipients.

May 9, 2026Transplant Infectious Disease

Epidemiology and Outcomes of Cryptococcal Infections in Liver Transplant Recipients: A Retrospective Cohort Study at a US Academic Center

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Authors

RSRachel SiglerUniversity of Kansas Medical Center CHChloe HaniganUniversity of Kansas ARAtikur RahmanUniversity of Kansas Medical Center

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Implication

Retrospective cohort study identifies risk factors and outcomes of cryptococcal infections in liver transplant recipients, suggesting geographic exposure influences risk.

Key Points

This study aims to identify predictors and outcomes of cryptococcal infections in liver transplant recipients.
Retrospective cohort study of 346 liver transplant recipients at a US academic center.
Used univariate logistic regression to analyze associations between clinical variables and cryptococcal infection.
Analyzed factors such as immunosuppression patterns and geographic location related to infection risk.
3.6% of patients developed cryptococcosis within 1 year post-transplant.
Rural residency associated with increased risk (OR 0.305; 95% CI 0.095-0.985; p = 0.047).
Early infection (< 45 days post-transplant) linked to shorter median survival of 382 days.

Cite This Study

Sigler et al. (2026) studied this question.

synapsesocial.com/papers/69fed021b9154b0b828771a5 https://doi.org/10.1111/tid.70231

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Implication

Retrospective cohort study identifies risk factors and outcomes of cryptococcal infections in liver transplant recipients, suggesting geographic exposure influences risk.

Epidemiology and Outcomes of Cryptococcal Infections in Liver Transplant Recipients: A Retrospective Cohort Study at a US Academic Center

Discussion

Member takes

Implication

Key Points

Cite This Study

Epidemiology and Outcomes of Cryptococcal Infections in Liver Transplant Recipients: A Retrospective Cohort Study at a US Academic Center

Discussion

Member takes

Implication

Key Points

Cite This Study

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