What question did this study set out to answer?

This research investigates the relationship between menstrual blood microbiological profiles and endometrial receptivity in patients undergoing frozen embryo transfer.

May 9, 2026DiagnosticsOpen Access

Microbiological Profiling of Menstrual Blood Aspirated from the Uterus in Patients Undergoing Frozen Embryo Transfer

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Authors

MJMark JainLomonosov Moscow State University EMElena Mladova PZPavel ZalepaevLomonosov Moscow State University

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Implication

Randomized trial evaluates microbiological profiles of menstrual blood and outcomes in patients undergoing frozen embryo transfer, suggesting new diagnostic possibilities.

Key Points

This research investigates the relationship between menstrual blood microbiological profiles and endometrial receptivity in patients undergoing frozen embryo transfer.
Menstrual blood was collected from 98 individuals scheduled for frozen embryo transfer.
DNA was extracted from menstrual sediment and analyzed using a multiplex quantitative PCR assay for microbial identification.
The study assessed the presence of 28 microbial taxa and 3 Herpesviridae viruses.
Bacterial DNA was detected in 75.5% of samples with no significant associations between individual microbial taxa and ET outcomes.
Candida spp. and Enterobacteriaceae were exclusively found in patients with negative ET outcomes (p = 0.028).
Patients with recurrent implantation failure had lower Lactobacillus spp. abundance compared to others (0.0 vs. 2.8%, p = 0.024).

Cite This Study

Jain et al. (2026) studied this question.

synapsesocial.com/papers/69fed0e2b9154b0b82878058 https://doi.org/10.3390/diagnostics16091403

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Implication

Randomized trial evaluates microbiological profiles of menstrual blood and outcomes in patients undergoing frozen embryo transfer, suggesting new diagnostic possibilities.

Microbiological Profiling of Menstrual Blood Aspirated from the Uterus in Patients Undergoing Frozen Embryo Transfer

Discussion

Member takes

Implication

Key Points

Cite This Study

Microbiological Profiling of Menstrual Blood Aspirated from the Uterus in Patients Undergoing Frozen Embryo Transfer

Discussion

Member takes

Implication

Key Points

Cite This Study

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