Synthesis of (Z)-6-Heneicosen-11-one, a Possible Pheromone Component of the Hickory Tussock Moth, Lophocampa caryae

Peter Mayo; Sumudu Deepa Abeysekera

doi:10.3390/m2171

May 6, 2026MolbankOpen Access

Synthesis of (Z)-6-Heneicosen-11-one, a Possible Pheromone Component of the Hickory Tussock Moth, Lophocampa caryae

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Key Points

The aim is to synthesize (Z)-6-heneicosen-11-one, a potential pheromone for the hickory tussock moth.
Developed a four-step synthesis procedure with a 39% yield
Incorporated a protecting group in a six-step synthesis with a 28% yield
Compared synthesis methods with existing literature
Achieved an overall yield of 39% with the new four-step procedure
Six-step method with protecting group yielded 28%
Synthesis techniques are comparable to existing methods in literature

Implication

Synthesis demonstrates new procedures for producing a pheromone in Lophocampa caryae, suggesting practical applications in pest management.

Abstract

The compound (Z)-6-heneicosen-11-one, a possible pheromone component of the hickory tussock moth, Lophocampa caryae, and a known pheromone component of the Douglas fir tussock moth, Orgyia pseudotsugata, was synthesized by a new four-step procedure with a 39% overall yield and a six-step procedure incorporating a protecting group with a 28% overall yield. This new synthesis is comparable to other similar syntheses for this molecule in the literature.

Synthesis of (Z)-6-Heneicosen-11-one, a Possible Pheromone Component of the Hickory Tussock Moth, Lophocampa caryae

Key Points

Implication

Abstract

Discussion

Cite This Study

Synthesis of (Z)-6-Heneicosen-11-one, a Possible Pheromone Component of the Hickory Tussock Moth, Lophocampa caryae

Key Points

Implication

Abstract

Discussion

Cite This Study

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