The working lives of neuronal 5-HT2A receptors from the outside in

Aneesah Jabar; Mikayla Pinto; Terry Hébert

doi:10.1039/d6cb00014b

January 1, 2026RSC Chemical BiologyOpen Access

The working lives of neuronal 5-HT2A receptors from the outside in

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Key Points

This research investigates the vital functions of 5-HT2A receptors in neuronal signalling and their implications in brain plasticity.
Evaluated the roles of 5-HT2A receptors in neuronal signalling networks.
Examined the impact on brain plasticity in relation to treatment approaches.
Demonstrated critical involvement of 5-HT2A receptors in regulating neuronal signalling.
Highlighted their potential therapeutic role in addressing resistant forms of depression.

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Implication

Reveals the impact of 5-HT2A receptors on neuronal signalling in depression, indicating their therapeutic potential.

Abstract

5-HT2A receptors have been shown to play critical roles in regulating neuronal signalling networks and brain plasticity. They have become important targets for the treatment of resistant forms of depression...

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Jabar et al. (2026) studied this question.

synapsesocial.com/papers/69fed140b9154b0b8287875e https://doi.org/10.1039/d6cb00014b

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The working lives of neuronal 5-HT2A receptors from the outside in

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The working lives of neuronal 5-HT2A receptors from the outside in

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