Body Adiposity and Endothelial Dysfunction Assessed By Laser Speckle Contrast Imaging in Obese and Overweight Individuals With Suboptimal Vitamin D Status: Sex Differences

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Key Points

The study aims to evaluate the relationship between body adiposity and endothelial function in obese individuals with suboptimal vitamin D levels.
Cross-sectional design involving participants aged 40-69 years with BMI 25-40 kg/m².
Participants were categorized based on median vitamin D levels into Suboptimal and Lower vitamin D groups.
Anthropometric indices and vascular function were assessed using imaging techniques.
Men showed greater endothelial dysfunction compared to women in the same vitamin D categories.
Lower vitamin D levels correlated with worse vascular function, particularly in obese participants.
Body adiposity was found to have a significant impact on vascular health, with sex differences noted.

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Cross-sectional study assesses vascular and autonomic function in obese individuals with low vitamin D, indicating health risks may vary by sex.

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Faria et al. (2026) studied this question.

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