Clinical Meaning Drift and Dynamic Disease: Why Fragmented Medical Knowledge Needs a Shared Language of Transition. Capture Note / Conceptual Note — URM Series

This Capture Note / Conceptual Note examines clinical meaning drift in dynamic disease and argues that fragmented medical knowledge requires a shared language of transition. Modern medicine contains extensive knowledge across specialties, biomarkers, organ systems, guidelines, imaging, AI systems, and clinical traditions. However, the dynamic relationships between these observations are often lost when knowledge moves between systems. Within the Universal Resonance Model (URM), this note proposes that disease should be interpreted not only through static categories, but through timing, instability, coupling, phase, transition, recovery, and system state. The note argues that clinical meaning can drift when terms, signals, or categories move across specialties, languages, clinical teams, regulatory contexts, or AI systems. A term may remain scientifically correct while its operational meaning shifts. This work is relevant to dynamic medicine, clinical interpretation, specialty fragmentation, medical language, AI in healthcare, systems medicine, and the development of transition-aware clinical reasoning.