Key result
Intraluminal thrombus presence and thickness are linked to lower metabolic activity in AAA walls.
Why the study?
Does intraluminal thrombus (ILT) thickness affect 18F-FDG PET uptake in the abdominal aortic aneurysm wall?
Observational
Does intraluminal thrombus (ILT) thickness affect 18F-FDG PET uptake in the abdominal aortic aneurysm wall?
p-value: p=0.046
18F-FDG PET imaging demonstrates that metabolic activity in the AAA wall is decreased compared to nondilated regions, an effect exacerbated by intraluminal thrombus thickness.
BACKGROUND: F-fluorodeoxyglucose and ILT presence and characteristics in AAA. METHODS: F-fluorodeoxyglucose uptake. RESULTS: =0.046). In both the ILT and thrombus-covered wall, TBR decreased with increasing ILT thickness. CONCLUSIONS: Decreased metabolic activity as per 18-fluorodeoxyglucose positron emission tomography is observed in the AAA wall compared with the nondilated abdominal region. This effect is exacerbated by local thrombus presence and thickness, suggesting that ILT contributes to the further degradation of the aortic wall in the diseased region.
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Bragulat-Arévalo et al. (2026) conducted an observational in Abdominal Aortic Aneurysms. Intraluminal thrombus (ILT) presence and thickness vs. Nondilated abdominal region / absence of thrombus was evaluated on 18F-fluorodeoxyglucose uptake (metabolic activity) (p=0.046). Intraluminal thrombus presence and thickness exacerbated the decreased metabolic activity on 18F-FDG PET observed in the abdominal aortic aneurysm wall compared with the nondilated region (P=0.046).
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