Single-Atom Nanozymes in Analytical Chemistry: Opportunities and Challenges

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. Additionally, their role in miniaturized analytical devices, such as lab-on-a-chip systems, showcases their compatibility with portable diagnostic tools, ensuring quick and reliable analysis in real-world settings. Still, challenges such as fabrication complexity, stability under various environmental conditions, and high material costs remain barriers to widespread adoption. The article also discusses the integration of SANs with advanced data analytics, such as machine learning and artificial intelligence, to enhance sensor performance. Despite these challenges, the transformative potential of SANs in analytical chemistry promises significant advances in both molecular detection and environmental sensing.