Why the study?
Does the anterior cingulate cortex mediate context-driven modulation of autonomic cardiovascular arousal during cognitive and motor tasks?
Population
3 patients with focal damage involving the anterior cingulate cortex (ACC) and 147 normal subjects
Comparison
Effortful cognitive and motor tests vs Normal subjects (for the lesion patients)
Design
Case-control
Authors
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ACC lesions may impair autonomic arousal; extends neuroimaging data on ACC mediation but remains hypothesis-generating without altering practice.
Does the anterior cingulate cortex mediate context-driven modulation of autonomic cardiovascular arousal during cognitive and motor tasks?
Converging neuroimaging and clinical findings suggest that the anterior cingulate cortex mediates context-driven modulation of bodily arousal states, including autonomic cardiovascular control.
Critchley et al. (2003) studied this question.
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